Reproducibility: Standardize antibodies used in research
نویسندگان
چکیده
منابع مشابه
Reproducibility in research
Progress in biomedical research depends in part on being able to build on the findings of other researchers - and thereby on being able to apply others' methods to your own research. However, most of us have struggled to understand how to repeat or adapt another researcher's study because of minimal or missing details in the Methods section of a published paper. In expensive and complex experim...
متن کاملWhat does research reproducibility mean?
The language and conceptual framework of "research reproducibility" are nonstandard and unsettled across the sciences. In this Perspective, we review an array of explicit and implicit definitions of reproducibility and related terminology, and discuss how to avoid potential misunderstandings when these terms are used as a surrogate for "truth."
متن کاملOpen Science and Research Reproducibility
Many scientists, journals and funders are concerned about the low reproducibility of many scientific findings. One approach that may serve to improve the reliability and robustness of research is open science. Here I argue that the process of pre-registering study protocols, sharing study materials and data, and posting preprints of manuscripts may serve to improve quality control procedures at...
متن کاملReproducibility in Research: Systems, Infrastructure, Culture
The reproduction and replication of novel results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the issues closely revolve around the ability to implement novel algorithms and models. Taking an approach from the literature and applying it to a new codebase frequently requires local knowledge mi...
متن کاملThe Economics of Reproducibility in Preclinical Research
Low reproducibility rates within life science research undermine cumulative knowledge production and contribute to both delays and costs of therapeutic drug development. An analysis of past studies indicates that the cumulative (total) prevalence of irreproducible preclinical research exceeds 50%, resulting in approximately US$28,000,000,000 (US$28B)/year spent on preclinical research that is n...
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ژورنال
عنوان ژورنال: Nature
سال: 2015
ISSN: 0028-0836,1476-4687
DOI: 10.1038/518027a